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Clinical Trials

Advancing novel candidates with the highest likelihood of driving significant benefit for patients.

We’re committed to evolving immunology. Our pipeline includes programs that are targeted to address highly prevalent inflammatory diseases. Our goal is to drive meaningful advances for patients with these diseases, designing all our programs to deliver best-in-class profiles.

STUDY
TRIAL OVERVIEW
Program:
EVO756-CIU001
Indication:
Chronic Inducible Urticaria (CINDU)
Status:
Phase 2a, Ongoing

EVO756-CIU001 is a Phase 2a, multi-center, open-label, within-subject controlled study evaluating EVO756 in adults with chronic inducible urticaria (either cold urticaria or symptomatic dermographism). All participants will receive EVO756, daily for a four-week treatment period. Patients will be evaluated for safety and efficacy at weekly visits during treatment and return to the clinic for final assessments two weeks following the last dose of study drug.

For additional information about the trial, please visit clinicaltrials.gov using the identifier NCT06603220.

Program:
EVO756-CSU001
Indication:
Chronic Spontaneous Urticaria (CSU)
Status:
Phase 2b, Ongoing

EVO756-CSU001 is a Phase 2b, randomized, placebo-controlled, multi-center study assessing EVO756, at multiple doses, in adults with chronic spontaneous urticaria. Participants will receive EVO756 or placebo for a 12-week treatment period and be evaluated for safety and efficacy at the clinical study site during the treatment period. Patients will return to the clinic for final assessments 2 weeks following the last dose of study drug.

For additional information about the trial, please visit clinicaltrials.gov using the identifier NCT06873516.

Program:
EVO301-AD001
Indication:
Atopic Dermatitis
Status:
Phase 2a, Ongoing

EVO301-AD001 is a Phase 2a, randomized, placebo-controlled, multi-center study evaluating EVO301 in adults with atopic dermatitis. Patients will be administered two intravenous treatments of EVO301 or placebo and followed for safety and efficacy over a 12-week study period.

For additional information about the trial, please visit clinicaltrials.gov using the identifier NCT06723405.

Expanded Access Policy

Currently, Evommune’s investigational therapies are not available on an expanded access or right-to-try basis for new patients. In the event Evommune decides to consider expanded access or right-to-try use, Evommune will evaluate and respond to each request that it receives on a case-by-case basis. For more information on Evommune’s investigational therapies and ongoing clinical trials, please visit clinicaltrials.gov.

We are focused on novel therapies that target the drivers of chronic inflammatory disease.